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Gluten Intolerance :: The Ten Most Common Symptoms

Over the last few years, the demand for gluten-free foods has skyrocketed. In fact, an estimated one in five Americans actively tries to include gluten-free foods in their diet. For some, eating gluten-free is viewed as a ticket to weight loss and boosted energy. For others, it’s just securing a seat at the popular table (since going gluten-free is all the rage right now). For many people, though, avoiding gluten-laden foods is a medical necessity.

Gluten is a type of protein found in wheat, barley, and rye. It helps give bread its airy and fluffy texture. It’s also a key stabilizing ingredient in many processed foods. While there’s no doubt gluten is lurking in some of your favorite pantry staples, it’s estimated that as much as 15 percent of the US population has trouble when consuming the controversial protein. Additionally, as many people who are already diagnosed, there are even more suffering from gluten intolerance and have no idea.

Celiac Disease

Celiac Disease (CD) is a very serious autoimmune disease that affects about one percent of the American population. If someone suffers from celiac, consuming even trace amount of gluten can be extremely problematic. That’s because the body perceives gluten as an invader and triggers an immune response that damages the small intestines. Over time, these attacks cause damage to the villi (small finger-like projections) lining the intestine. This, in turn, makes it hard for the body to properly absorb nutrients. *More signs and symptoms of celiac disease below.

Right now, the only treatment for Celiac sufferers is a strict, gluten-free diet.

Taking a simple blood test can help determine if you have Celiac Disease, however, if tests come back negative, there’s still a chance you have a gluten sensitivity / intolerance and unfortunately an upper Endoscopy with an intestinal biopsy is really the best method of detection.

Non-Celiac Gluten Sensitivity

Non-Celiac Gluten Sensitivity (NCGS) is a milder form of gluten intolerance that can still cause major health problems. While it’s harder to diagnose, research estimates that 18 million Americans suffer from gluten sensitivity. That’s nearly six times the amount of Americans who have Celiac Disease.

Both Celiac and Non-Celiac Gluten Sensitivity can cause serious symptoms that affect the entire body:

1) Digestive Issues

After you indulge in a piece of pizza, a bowl of pasta, or a fluffy muffin, does your stomach start acting up? Gas, bloating, stomach pain, constipation, and diarrhea are all common signs of gluten intolerance. According to research studies, some people experience digestive issues within a few hours of eating gluten foods, while others may not notice symptoms until the following day.

Along with constipation and diarrhea, people who have Celiac Disease may also experience pale and foul-smelling stool. This is a result of poor nutrient absorption (as I mentioned earlier).

2) Brain Fog

Do you ever feel like you can’t think clearly? Are you more forgetful than you used to be? Do you get confused easily? Do you have trouble focusing? If so, you’re most likely experiencing a bout of brain fog.

While this form of cognitive impairment can be triggered by a number of things — such as stress, lack of sleep, or hormone changes — it may be a sign your body can’t handle gluten. Nearly 40 percent of gluten-intolerant individuals report experiencing “brain fog.” Additionally, according to Celiac.org, Celiac Disease patients show major improvement once they begin eating a gluten-free diet.

To date, there have been a few studies that have taken a closer look at how gluten affects the brain/cognitive ability. In one study, Mayo Clinic researchers found a link between celiac disease and forms of cognitive decline (such as Dementia). Keith Josephs, M.D., Mayo Clinic neurologist and study investigator said:

“This is the largest case series to date of patients demonstrating cognitive decline within two years of the onset of Celiac Disease symptom onset or worsening.”

3) Anxiety, Depression, and Mood Swings

Speaking of gluten affecting our minds, researchers have found people who are gluten intolerant can be more susceptible to anxiety, depression, and mood swings (especially if the person is left undiagnosed and continues to consume gluten-laden foods). Researchers have a few possible explanations as to why gluten may affect mood.

Seratonin Levels – Studies show that gluten can affect the amount of serotonin in our body. Serotonin is a neurotransmitter in the brain that allows cells to communicate and regulates mood. It’s often referred to as the “happy hormone.” In one study, rats fed wheat showed decreased serotonin levels.

Gluten Exorphins – Exorphins are opioid peptides that come from outside the body (for example, gluten after it’s been partially digested). These peptides can affect the central nervous system and increase the risk of depression.

Gut Bacteria – Research shows patients with Celiac Disease have unbalanced gut bacteria, which is extremely detrimental to mental health (as well as overall health). In multiple case studies with mice, researchers were able to completely alter the mice’s behavior by changing their gut bacteria. The mice that had balanced gut bacteria were less anxious, more adventurous, and seemed to be in a better mood. Researchers at UCLA found the same effect on humans. While it’s still unknown, gluten itself is believed to cause the bacterial imbalance, rather than the Celiac Disease itself.

4) Fatigue

It’s normal to feel tired after a night of tossing and turning or a stressful day, but if you’re chronically fatigued then it’s time to figure out why. Numerous studies link fatigue to gluten intolerance. Studies show between 60–82 percent of people with gluten-intolerance commonly experience fatigue, especially after eating foods that contain gluten.

5) Headaches

Headaches are pretty common and can be triggered by a number of different things — from dehydration to stress. According to researchers, though, people who suffer from gluten-intolerance may be more prone to migraines. In one study by the American Headache Society, researchers collected data from 502 patients with either celiac disease, Irritable Bowel Disease (IBD), or gluten sensitivity. They also included a control group. They found chronic headaches reported by 56 percent of people with gluten sensitivity, 30 percent of people with celiac disease, 23 percent of people with IBD, and 14 percent of control subjects.

Researchers warn if you have chronic and severe headaches without any apparent cause, gluten may be the culprit.

6) Skin Problems

About 15-25 percent of people with Celiac Disease experience a severe, itchy, blistering skin condition called Dermatitis herpetiformis (DH). This skin manifestation of Celiac is part of the abnormal immune response to gluten and typically occurs on the elbows, knees, and buttocks. Treatment consists of a lifelong gluten-free diet and experts say it may take up to two years to gain total control of the condition.

DH isn’t the only way gluten can affect the skin. Several other skin diseases have been shown to improve from ditching gluten. They include Eczema, Psoriasis, Acne, Alopecia Areata, and chronic Urticarial.

7) Autoimmune Disorders

Various studies reveal people who suffer from Celiac Disease (which is an auto-immune disease) are more prone to developing other auto-immune disorders such as Hashimoto’s Thyroiditis, Rheumatoid Arthritis, Multiple Sclerosis, Ulcerative Colitis, and Lupus. Additionally, according to researchers:

“Increased prevalence of Celiac Disease has been found in patients with autoimmune thyroid disease, Type 1 Diabetes Mellitus, autoimmune liver diseases, and inflammatory bowel disease.”

If you’ve already been diagnosed with an auto-immune disease and experience some of the other symptoms on this list, you may want to get tested for celiac disease or try adopting a gluten-free diet.

8) Iron-Deficiency Anemia

Iron-deficiency anemia is the single most prevalent nutritional deficiency around the globe. It’s also one of the first warning signs of Celiac Disease. Earlier in this article, I told you that Celiac Disease can damage the intestines and lead to poor nutrient absorption. When your body doesn’t properly absorb iron it interferes with the production of hemoglobin, which is necessary to transport oxygen throughout the body.

In one study, researchers set out to determine the prevalence of celiac disease in patients with iron deficiency anemia. Out of 84 patients, a little more than 7 percent tested positive for celiac. They were then put on a gluten-free diet. Shortly after, researchers noticed their hemoglobin levels improved drastically. This shows a direct connection to gluten!

9) Joint Pain

For people who are gluten intolerant, indulging in a gluten-filled meal can cause an inflammatory response in the body. That inflammation can lead to swelling and pain, particularly in the joints. If you are experiencing joint pain, try eliminating gluten from your diet and see if you notice a difference.

10) Leg and Arm Numbness

Researchers also link gluten intolerance to neuropathy, a disorder that causes numbness in the hands and feet. According to researchers, neurologic complications are estimated to occur in 10% of celiac patients, with peripheral neuropathy being one of the most common problems.

Think You’re Gluten Intolerant? Try an Elimination Diet

One of the best ways to determine if you are gluten intolerant is to try an elimination diet. The elimination diet is an eating plan that lasts for around a month or so and requires you to slowly eliminate certain foods from your plate — in this case gluten. A recent study showed that after two years on a gluten free diet, only 34% of patients with celiac disease had mucosal recovery, or a healed gut.

While it can take six months or longer for mucosal recovery to occur, a healed gut. Most will begin experiencing relief in just a few weeks and the longer you go gluten-free, the greater the benefit.

In order to achieve accurate results, you will need to eliminate 100 percent of the gluten from your diet. That means you will need to be very diligent about reading ingredient labels. Did you know there is gluten in ketchup, mayonnaise, many salad dressings, soy sauce, some soups, some veggie burgers, bouillon cubes, some chewing gums, candy, and anything malt?

Once you’ve gone gluten-free for about a month, reintroduce it back into your diet. If you start to feel worse after you reintroduce it into your diet then you’ll know gluten is an issue.

If you suspect you are gluten-intolerant, you’re also encouraged to meet with your doctor.

Going Gluten-Free

While going gluten-free may seem like a nearly impossible task, today, there are plenty of healthy and delicious options out there for you. While you should stick to whole foods (like fruits, vegetables, and lean proteins), you don’t have to give up delicious desserts and baked goods. Rather, start experimenting with new flours — like coconut, almond, quinoa, and oat flours.

Remember, if you are truly gluten intolerant, even consuming trace amounts of gluten from cross contamination can cause a painful immune reaction. Along with reading food labels carefully, check with your doctor to make sure there aren’t any trace amounts of gluten found in your medications or supplements.

As you’ve learned, gluten intolerance can affect nearly every tissue in the body, including the brain, skin, endocrine system, stomach, liver, blood vessels, smooth muscles, and even the nuclei of cells. CD and NCGS are associated with an astonishing variety of diseases, including schizophrenia, epilepsy, Type 1 diabetes, osteoporosis, dermatitis, Psoriasis, Hashimoto’s hypothyroidism, and peripheral neuropathy. Because the range of symptoms associated with gluten intolerance is so broad and nonspecific (i.e. can be attributed to any number of conditions), many patients and doctors don’t suspect gluten may be the cause.

Left untreated, gluten intolerance can lead to serious and debilitating health conditions, so discovering and addressing a sensitivity can save your future health as well as improve your current quality of life.

To learn how to get started with a gluten free diet we encourage you to visit Gluten.org and EatingWell.com.

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