RAD140 increases lean muscle mass, strength and endurance as well as sexual performance in men.

What is RAD 140?

RAD140, also known as Testolone, is a peptide that is popular for its muscle-building effects. RAD140 belongs to a class of compounds called selective androgen receptor modulators, or SARMs.

SARMs work by binding to androgen receptors that are found in different areas of the body. Normally these receptors interact with androgens, which are a group of steroid hormones. Androgens like testosterone, dihydrotestosterone, and androstenedione are naturally produced by the body.

SARMs and testosterone have similar effects because they work on the same receptor. Some of these effects include influencing the muscles, bones, and the liver.

The advantage of SARMs is that they are selective about where they work. They mostly target muscle and bone tissues while having minimal effects on other organs. This allows SARMs to potentially treat hormone-related or muscle-wasting disorders with fewer side effects.

Additionally, the structure of RAD140 is also very different from that of steroid hormones like testosterone. This means the body isn’t able to convert RAD140 into other hormones like estrogen that may have undesirable effects.

RAD140 works by selectively stimulating androgen receptors in the body thereby stimulating muscle growth by promoting the development of muscle cells and proteins. It targets receptors in the muscle and bone and has little to no effect on the reproductive organs.

RAD140 has become popular among men with low testosterone levels who wish to avoid testosterone replacement therapy but are looking to maintain their physical and sexual performance.

Androgens also play an important role in protecting the brain. They can increase brain cell growth, improve memory, and decrease amyloid beta accumulation. Amyloid beta proteins are believed to be the main cause of Alzheimer’s disease [R].

In a study in rats, RAD140 activates receptors in regions of the brain that are injured. This triggers a signal called the MAPK pathway that helps protect cells against injury from amyloid beta. Additionally, RAD140 and testosterone were equally effective at protecting against neurotoxins [R].

Research is currently investigating RAD140’s potential role in fighting breast cancer and showing promising results in a common form of the disease called androgen and estrogen receptor positive (AR/ER+) [R,R]. AR/ER+ is sensitive to hormones and medications that affect these receptors, like SARMs, may have cancer-fighting potential [R].

In a cell study, RAD140 stopped the growth of AR/ER+ breast cancer cells by blocking the effects of estrogen [R].

Specifically, RAD140 appears to suppress the ESR1 gene. This gene is responsible for creating estrogen receptors. Without sufficient receptors, estrogen may be left powerless and inactive [R].

Benefits of RAD 140

• Decreased body fat
• Increased muscle mass
• Increased strength
• Improved energy & endurance
• Protects brain cells
• Improves fat burning

Potential Side Effects of RAD 140

Based on how SARMs work, RAD140 should cause fewer unwanted effects than testosterone. That said, RAD140 still has the potential to cause testosterone-related side effects. These may include [R, R]:

• Breast tenderness/growth in men
• Abnormal body hair growth in women
• Changes in sex drive
• Male pattern baldness/hair loss
• Mood swings and anxiety/depression
• Nausea and vomiting

Bodybuilders have reported hair loss as a side effect, which is reversed once they stop taking RAD140. It’s worth mentioning the bodybuilders tend to take much higher dosages than are recommended and this is far less common when taking standard dosages.

Peptide Therapies

The peptide therapy protocols (Amino Acid Analogs) prescribed by our providers are also known as secretagogues (pronounced se-creta-gog), a substance that promotes secretion. These amino acid chains communicate with the body to produce or release growth hormone. Hence a secretagogue causes the body’s own natural processes to produce growth hormone. Secretagogues do not act as growth hormones but rather stimulate the pituitary gland to secrete your stored growth hormone. The subcutaneous injection route of growth hormone stimulation is a preferred route to help slow down age and environmental reductions in growth hormone levels.